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Home Archive Identification and Qualitative Phytochemical Evaluation of Alcoholic Root Extract of Plumbago Zeylanica- An Oriental Medicinal Herb
Details for Identification and Qualitative Phytochemical Evaluation of Alcoholic Root Extract of Plumbago Zeylanica- An Oriental Medicinal Herb
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NameIdentification and Qualitative Phytochemical Evaluation of Alcoholic Root Extract of Plumbago Zeylanica- An Oriental Medicinal Herb
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Original article

Sivakumar Vijayaraghavalu1*#, Kulanthaivel Thalakompudur Marappagounder1, Noohu Abdulla Khan2 and Munish Kumar3

1Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University (KKU), Abha, Kingdom of Saudi Arabia (KSA)

2Department of Clinical Pharmacy, College of Pharmacy, KKU, Abha, KSA

3Department of Biochemistry, Allahabad University, Allahabad, Uttar Pradesh, India

Abstract:

Man has relied on plants as a source of therapeutic agents for centuries. Today, with the specter of antibiotic resistance, emerging infectious diseases, and cancers, phytochemicals continue to provide new structural leads for chemotherapeutic industry. Roots of Plumbago zeylanica, commonly named as white leadwort was used to treat various ailments in oriental medicines including cancer. The two most common Plumbago species in India are Plumbago zeylanica and Plumbago indica. Due to their morphological similarity the roots of two species are often misidentified and adulterated. Hence, this study was carried out to properly identify the roots of Plumbago zeylanica employing light microscopy and qualitatively characterize the phytochemicals in it. In addition, thin- layer chromatography (TLC), ultraviolet/visible- and infrared- spectroscopy was done to identify and quantify the active principle (plumbagin) in roots of Plumbago zeylanica procured from Chennai, India. The anatomical sectioning showed the structural difference between the roots of two species. The phytochemical evaluation revealed presence of various pharmacologically active components such as flavonoids, tannins, saponins and phytosterols. The TLC and UV studies showed the presence of plumbagin at the concentration of 0.1% w/w in the plant extract. Further infrared spectroscopy confirmed the presence of plumbagin in alcoholic root extract of Plumbago zeylanica. Presence of beneficial phytochemicals justifies its wide use as antioxidant, cardiotonic, anticancer, antibacterial and as chemopreventive agent against numerous pathological conditions in several traditional medical systems practiced across Asia.

Keywords: Plumbago zeylanica, Plumbago indica, plumbagin, IR, oriental herb, flavonoids, antioxidants, UV/visible.

Address reprint to:

*Sivakumar Vijayaraghavalu, Ph.D.

Assistant Professor, Department of Pharmaceutical Chemistry, College of Pharmacy, King Khalid University, Abha, Kingdom of Saudi Arabia, P.O.Box:1882, Postal code:6144. Email: livshiva@gmail.com

Published under Creative Commons Attribution (CC BY) license.

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Created On: 08/22/2017 00:00
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